Can blood pressure lowering reduce CV risk across the risk spectrum?
Prof Kazem Rahimi (University of Oxford, United Kingdom) joins Dr Harriette Van Spall (McMaster University, Canada) for a Late-breaker Discussion recorded at ESC Congress 2026.
The discussion focuses on Blood Pressure-Lowering Treatment Across the Spectrum of Cardiovascular Risk, an individual participant-level meta-analysis examining whether pharmacological blood pressure-lowering therapy can reduce major cardiovascular events across a broad range of baseline cardiovascular risk profiles.
Drawing on data from approximately 350,000 participants enrolled in randomised controlled trials, the analysis evaluated antihypertensive therapies including ACE inhibitors, ARBs, beta-blockers, calcium-channel blockers and diuretics compared with less intensive treatment approaches or placebo/usual care. The study addresses cardiovascular disease prevention across both primary and secondary prevention settings.
Key topics:
Cardiovascular risk-based prevention strategies
Blood pressure-lowering therapy
Individual participant-level meta-analysis
Primary and secondary prevention
Stroke prevention
Coronary heart disease
Heart failure prevention
ESC Congress 2026 Hot Line science
Hypertension management
Population-level cardiovascular risk reduction
References:
ESC Congress 2026 Presentation] Blood Pressure-Lowering Treatment Across the Spectrum of Cardiovascular Risk. \[PubMed] *A meta-analysis of the long-term effects of antihypertensive therapy on the risk of major cardiovascular disease across 51 randomized trials* (PMID: 42387214). Recorded at ESC Congress 2026, Munich, Germany. Editor: SD Videographer: MB Independently produced by Radcliffe Cardiology in partnership with Dr Harriette Van Spall. \#ESC2026 #Hypertension #BloodPressure #CardiovascularRisk #CardiovascularPrevention #KazemRahimi #HarrietteVanSpall #Cardiology #PreventiveCardiology #LateBreakerDiscussion #ESCCongress2026
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This content is intended for healthcare professionals only.
Radcliffe brings medical knowledge, insight and innovation to life for CV clinicians around the world, using our communications & creative expertise, our platforms and connections across the community to help transform theory into practice faster.
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Prof Kazem Rahimi (University of Oxford, United Kingdom) joins Dr Harriette Van Spall (McMaster University, Canada) for a Late-breaker Discussion recorded at ESC Congress 2026.
The discussion focuses on Blood Pressure-Lowering Treatment Across the Spectrum of Cardiovascular Risk, an individual participant-level meta-analysis examining whether pharmacological blood pressure-lowering therapy can reduce major cardiovascular events across a broad range of baseline cardiovascular risk profiles.
Drawing on data from approximately 350,000 participants enrolled in randomised controlled trials, the analysis evaluated antihypertensive therapies including ACE inhibitors, ARBs, beta-blockers, calcium-channel blockers and diuretics compared with less intensive treatment approaches or placebo/usual care. The study addresses cardiovascular disease prevention across both primary and secondary prevention settings.
Key topics:
Cardiovascular risk-based prevention strategies
Blood pressure-lowering therapy
Individual participant-level meta-analysis
Primary and secondary prevention
Stroke prevention
Coronary heart disease
Heart failure prevention
ESC Congress 2026 Hot Line science
Hypertension management
Population-level cardiovascular risk reduction
References:
ESC Congress 2026 Presentation] Blood Pressure-Lowering Treatment Across the Spectrum of Cardiovascular Risk. \[PubMed] *A meta-analysis of the long-term effects of antihypertensive therapy on the risk of major cardiovascular disease across 51 randomized trials* (PMID: 42387214). Recorded at ESC Congress 2026, Munich, Germany. Editor: SD Videographer: MB Independently produced by Radcliffe Cardiology in partnership with Dr Harriette Van Spall. \#ESC2026 #Hypertension #BloodPressure #CardiovascularRisk #CardiovascularPrevention #KazemRahimi #HarrietteVanSpall #Cardiology #PreventiveCardiology #LateBreakerDiscussion #ESCCongress2026
Visit Radcliffe Cardiology: https://www.radcliffecardiology.com/
This content is intended for healthcare professionals only.
Radcliffe brings medical knowledge, insight and innovation to life for CV clinicians around the world, using our communications & creative expertise, our platforms and connections across the community to help transform theory into practice faster.
Like us on Facebook: https://www.facebook.com/RadcliffeCardiology
Follow us on X: https://x.com/radcliffeCARDIO
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